Selected Publications

Ineichen, C, Greter A, Baer M, Sigrist H, Sautter E, Sych Y, Helmchen F, Pryce, CR. (2020). Basomedial amygdala activity in mice reflects specific and general aversion uncontrollability. European Journal of Neuroscience, DOI: 10.1111/ejn.15090

Pryce CR. (2018). Comparative evidence for the importance of the amygdala in regulating reward salience. Current Opinion in Behavioral Sciences, 22C: 76-81.

Bergamini G, Mechtersheimer J, Azzinnari D, Sigrist H, Buerge M, Dallmann R, Freije R, Seifritz E, Ferger B, Suter T, Pryce CR. (2018). Mouse chronic social stress induces peripheral and brain immune activation, blunted mesolimbic dopamine function, and reduced interest in reward. Neurobiology of Stress, 8: 42-56. DOI: 10.1016/j.ynstr.2018.01.004

Just S, Chenard BL, Ceci A, Strassmaier T, Chong JA, Blair NT, Gallaschun RJ, del Camino D, Cantin S, D’Amours M, Eickmeier C, Fanger CM, Hecker C, Hessler DP, Hengerer B, Kroker KS, Malekiani S, Mihalek R, McLaughlin J, Rast G, Witek J, Sauer A, Pryce CR, Moran MM. (2018). Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice. PLOS ONE, 13(1): e0191225. DOI: 10.1371/journal.pone.0191225

Grandjean J, Azzinnari D, Seuwen A, Sigrist H, Seifritz E, Pryce CR.*, Rudin M* (2016). Chronic psychosocial stress in mice leads to changes in brain functional connectivity and metabolite levels comparable to human depression. NeuroImage, 142: 544-552.  DOI: 10.1016/j.neuroimage.2016.08.013

Klaus F, Paterna J-C, Marzorati E, Sigrist H, Götze L, Schwendener S, Bergamini G, Jehli E, Azzinnari D, Fuertig R, Fontana A, Seifritz E, Pryce CR. (2016). Differential effects of peripheral and brain tumor necrosis factor on inflammation, sickness, emotional behaviour and memory in mice. Brain, Behavior, and Immunity,58: 310-326. DOI: 10.1016/j.bbi.2016.08.001

Fuertig R, Azzinnari D, Bergamini G, Cathomas F, Sigrist H, Seifritz E, Vavassori S, Luippold A, Hengerer B, Ceci A, Pryce CR. (2016). Mouse chronic social stress increases blood and brain kynurenine pathway activity and fear behaviour: both effects are reversed by inhibition of indoleamine 2,3-dioxygenase. Brain, Behavior, and Immunity, 54: 59-72. DOI: 10.1016/j.bbi.2015.12.020

Habbas S, Santello M, Becker D, Stubbe H, Zappia G, Liaudet N, Klaus FR, Kollias G, Fontana A, Pryce CR, Suter T, Volterra A. (2015). Neuroinflammatory TNF impairs memory via astrocyte signaling. Cell, 163: 1730-1741. DOI: 10.1016/j.cell.2015.11.023

Azzinnari D, Sigrist H, Staehli S, Palme R, Hildebrandt T, Leparc G, Hengerer B, Seifritz E, Pryce CR. (2014). Mouse social stress induces increased fear conditioning, helplessness and fatigue to physical challenge together with markers of altered immune and dopamine function. Neuropharmacology, 85: 328-341. DOI: 10.1016/j.neuropharm.2014.05.039

Ineichen C, Sigrist H, Spinelli S, Lesch K-P, Sautter E, Seifritz E, Pryce CR. (2012). Establishing a probabilistic reversal learning test in mice: evidence for the processes mediating reward-stay and punishment-shift behaviour and for their modulation by serotonin. Neuropharmacology, 63: 1012-1021. DOI: 10.1016/j.neuropharm.2012.07.025

Pryce CR, Azzinnari D, Spinelli, S., Seifritz E, Tegethoff M, Meinlschmidt G. (2011). Helplessness: a systematic translational review of theory and evidence for its relevance to understanding and treating depression. Pharmacology & Therapeutics, 132: 242-267. DOI: 10.1016/j.pharmthera.2011.06.006