Experimental Stress and Depression Therapies (PD Dr. O. G. Bosch)

Depression and other stress-related disorders are among the most frequent mental health problems, causing a substantial degree of individual suffering and impact on worldwide health care systems. Current estimations see major depressive disorder as the leading cause for the global burden of disease in 2030. Although a wide spectrum of antidepressant treatments exist, the overall outcome is unsatisfying. Our main goals are to conduct human neuropsychopharmacological research that: (1) increases understanding of the neurobiological mechanisms underlying depression and other stress-related disorders, and (2) contributes to the discovery and development of novel, effective therapies for these pathologies.