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Our research group is an inter-disciplinary team of researchers and clinicians committed to advancing understanding of the brain and behavior in health and during affective and psychotic disorders. We use a variety of methods and approaches to elucidate the underlying neurobiology of neuropsychiatric symptoms, to examine biomarkers of psychopathology, predictors of treatment response, and to test novel therapeutic interventions, with an emphasis on the use of neuropsychological testing and pharmacologic challenges in combination with neuroimaging technologies.