Schizophrenia Research

Head: PD Dr. med. Stefan Kaiser


The main focus of the group is on the negative symptoms of schizophrenia and related disorders. Negative symptoms are strongly associated with impaired functioning and can be divided into the domains apathy/avolition and diminished expression.

In our research we employ a multi-level approach equally emphasizing psychopathological assessment, behavioral experiments and functional imaging. Current projects are assessing readouts on all these levels in patients with schizophrenia and related disorders. A particular emphasis lies on behavioral and neural aspects of decision-making in relation to negative symptoms. These readouts will be used to investigate possible causal mechanisms leading to negative symptoms and to assess effects of interventions on negative symptoms.

Further research interests of the group are cognitive functioning and remediation as well as concepts for optimizing treatment in first-episode psychosis. The common thread of the research is the focus on symptoms and other challenges that are highly relevant for long-term functional outcome and quality of life.